John 16:32-33 says, “Behold, the hour is coming, indeed it has come, when you will be scattered, each to his own home, and will leave me alone. Yet I am not alone, for the Father is with me. I have said these things to you, that in me you may have peace. In the world you will have tribulation. But take heart; I have overcome the world.”
Jesus spoke the words recorded in St. John chapter 16 during his last supper with his disciples. It was the night he would be betrayed by Judas. It was the night before he would be crucified for the sins of the world.